Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | DDX3X | O00571 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435778 | 0.91 | MAPT (0.47) | BIRC5MAPTSMN1; SMN2TP53POLB | |
| SCHEMBL6435783 | 0.91 | MAPT (0.47) | BIRC5MAPTSMN1; SMN2TP53POLB | |
| SCHEMBL6415384 | 0.87 | MAPT (0.40) | BIRC5MAPTSMN1; SMN2TP53POLB | |
| SCHEMBL6415379 | 0.87 | MAPT (0.40) | BIRC5MAPTSMN1; SMN2TP53POLB | |
| SCHEMBL6415960 | 0.85 | MAPT (0.41) | BIRC5MAPTSMN1; SMN2TP53POLB | |
| SCHEMBL6415964 | 0.85 | MAPT (0.41) | BIRC5MAPTSMN1; SMN2TP53POLB | |
| SCHEMBL6414183 | 0.84 | MAPT (0.40) | BIRC5MAPTSMN1; SMN2TP53POLB | |
| SCHEMBL6414195 | 0.84 | MAPT (0.40) | BIRC5MAPTSMN1; SMN2TP53POLB | |
| SCHEMBL3055383 | 0.80 | GAA (0.49) | BIRC5MAPTSMN1; SMN2POLBMAOA | |
| SCHEMBL6421048 | 0.80 | GAA (0.49) | BIRC5MAPTSMN1; SMN2POLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | 4SC AG (DE) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | NR5A2, NR1H2, NR2C2 | BIRC5 2525/4885MAPT 4420/4885SMN1; SMN2 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.