Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468382 | 0.89 | GAA (0.64) | KMT2AMEN1TSHRGLAGAA | |
| SCHEMBL14409571 | 0.87 | TSHR (0.70) | KMT2AMEN1TSHRGLAGAA | |
| SCHEMBL16823981 | 0.85 | MEN1 (0.60) | KMT2AMEN1NPC1L1KDM4EPOLB | |
| SCHEMBL6270590 | 0.85 | HPGD (0.73) | KMT2AMEN1NPC1L1POLBHPGD | |
| SCHEMBL314589 | 0.84 | TSHR (0.75) | KMT2AMEN1TSHRGLAGAA | |
| SCHEMBL4172039 | 0.84 | TSHR (0.67) | KMT2AMEN1TSHRGLAGAA | |
| SCHEMBL3339277 | 0.84 | TSHR (0.67) | KMT2ATSHRGLAGAAKDM4E | |
| SCHEMBL6973124 | 0.84 | GAA (0.73) | KMT2AMEN1TSHRGLAGAA | |
| SCHEMBL4598393 | 0.83 | TSHR (0.66) | KMT2AMEN1TSHRGLAGAA | |
| SCHEMBL988274 | 0.82 | MEN1 (0.66) | KMT2AMEN1GAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591222-A | Method for efficiently preparing fluoro-alkene amide | 江南大学 | 2022-06-07 | — | — | CN | disclosed |
| WO-2005058882-A1 | COMPOUNDS HAVING MORPHOLINYL AND PIPERIDINYL GROUPS FOR USE AS GLYT1 AND GLYT2 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058882-A1 | COMPOUNDS HAVING MORPHOLINYL AND PIPERIDINYL GROUPS FOR USE AS GLYT1 AND GLYT2 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |