Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 6/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.60 |
| ▸ | IKBKB | O14920 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16399092 | 0.88 | TARBP2 (0.75) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL6506172 | 0.88 | TARBP2 (0.58) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL2826477 | 0.88 | TARBP2 (0.58) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL2778345 | 0.88 | TARBP2 (0.70) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL4918154 | 0.85 | TARBP2 (1.00) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL2822458 | 0.84 | TARBP2 (0.54) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL27492410 | 0.82 | IKBKB (0.73) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL16005327 | 0.81 | TARBP2 (0.55) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL28297243 | 0.81 | TARBP2 (0.81) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL11620370 | 0.81 | TARBP2 (0.61) | TARBP2ALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |