Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6508000 | 0.91 | SMN1; SMN2 (0.44) | HPGDTSHRSMN1; SMN2CHEK2UTS2R | |
| SCHEMBL4834333 | 0.85 | DRD3 (0.49) | HPGDTSHRSMN1; SMN2KDM4EDRD2 | |
| SCHEMBL4833967 | 0.81 | TSHR (0.48) | HPGDTSHRSMN1; SMN2KDM4EDRD2 | |
| SCHEMBL4828371 | 0.80 | TSHR (0.53) | HPGDTSHRSMN1; SMN2KDM4EDRD2 | |
| SCHEMBL5760224 | 0.79 | HPGD (0.48) | HPGDTSHRSMN1; SMN2CHEK2DRD2 | |
| SCHEMBL4834405 | 0.78 | SMN1; SMN2 (0.52) | HPGDTSHRSMN1; SMN2KDM4EDRD2 | |
| SCHEMBL4834840 | 0.78 | TSHR (0.57) | HPGDTSHRSMN1; SMN2KDM4EDRD2 | |
| SCHEMBL4839715 | 0.77 | SMN1; SMN2 (0.49) | HPGDTSHRSMN1; SMN2KDM4EDRD2 | |
| SCHEMBL4839889 | 0.76 | HPGD (0.47) | HPGDTSHRSMN1; SMN2KDM4EDRD2 | |
| SCHEMBL14181485 | 0.76 | HPGD (0.47) | HPGDTSHRSMN1; SMN2KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097770-A1 | NOVEL HYDROXAMATES AS THERAPEUTIC AGENTS | PHARMACYCLICS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |