Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1330785 | 0.94 | — | — | |
| Bicarbonate SCHEMBL26137 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5982221 | 0.88 | — | — | |
| Bicarbonate SCHEMBL18420858 | 0.88 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL3394552 | 0.88 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL18280949 | 0.88 | — | — | |
| Bicarbonate SCHEMBL6322879 | 0.88 | — | — | |
| Bicarbonate SCHEMBL8469821 | 0.88 | — | — | |
| Bicarbonate SCHEMBL1603055 | 0.88 | — | — | |
| Bicarbonate SCHEMBL18191894 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119769-B2 | Complement depletion using recombinant human C-3 derivatives | PLS Design, GmbH (DE) | 2012-02-21 | — | — | US | disclosed |