Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.71 |
| ▸ | FNTB | P49356 | 17/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650468 | 1.00 | FNTA (0.71) | FNTAFNTBTHRBCACNA1GCACNA1H | |
| SCHEMBL648851 | 0.91 | FNTA (0.71) | FNTAFNTBTHRB | |
| SCHEMBL648852 | 0.91 | FNTA (0.71) | FNTAFNTBTHRB | |
| SCHEMBL653554 | 0.91 | FNTA (0.71) | FNTAFNTBTHRB | |
| SCHEMBL651288 | 0.90 | FNTA (0.71) | FNTAFNTBTHRB | |
| SCHEMBL651287 | 0.90 | FNTA (0.71) | FNTAFNTBTHRB | |
| SCHEMBL651451 | 0.85 | FNTA (0.67) | FNTAFNTBTHRB | |
| SCHEMBL651452 | 0.85 | FNTA (0.67) | FNTAFNTBTHRB | |
| SCHEMBL651191 | 0.85 | FNTA (0.67) | FNTAFNTBTHRB | |
| SCHEMBL650165 | 0.85 | FNTA (0.67) | FNTAFNTBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884113-B2 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-02-08 | — | — | US | claimed |
| US-20080194625-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2008-08-14 | — | — | US | claimed |
| US-20050014786-A1 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2005-01-20 | — | — | US | claimed |
| US-6590022-B1 | Emulsion polymerization, drying | WACKER-CHEMIE GMBH (DE) | 2003-07-08 | — | — | US | claimed |
| EP-1036101-B1 | METHOD FOR PRODUCING PROTECTIVE COLLOID-STABILISED VINYL AROMATIC-1.3-DIENE-COPOLYMERS | WACKER CHEMIE GMBH (DE) | 2001-08-16 | — | — | EP | claimed |
| EP-1023331-B1 | METHOD FOR PRODUCING POLYMERS STABILISED WITH PROTECTIVE COLLOIDS | WACKER CHEMIE GMBH (DE) | 2001-06-13 | — | — | EP | claimed |
| US-20180282440-A1 | PROCESS FOR PREPARING VINYL ACETATE-ETHYLENE COPOLYMERS BY EMULSION POLYMERIZATION | WACKER CHEMIE AG (DE) | 2018-10-04 | — | — | US | disclosed |
| US-8722788-B2 | Transparent TPU (thermoplastic polyurethanes)/PMMA (polymethyl (meth) acrylate) blends with improved low-temperature impact resistance | EVONIK ROEHM GMBH (DE) | 2014-05-13 | — | — | US | disclosed |
| US-8420709-B2 | Coating composition, (meth)acrylic polymer and monomer mixture for producing the (meth)acrylic polymer | EVONIK RÖHM GMBH (DE) | 2013-04-16 | — | — | US | disclosed |
| US-8119808-B2 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-21 | — | — | US | disclosed |
| US-8119734-B2 | Process for preparing aqueous dispersions | EVONIK ROEHM GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20110318595-A1 | COATING COMPOSITION, (METH)ACRYLIC POLYMER AND MONOMER MIXTURE FOR PRODUCING THE (METH)ACRYLIC POLYMER | EVONIK ROEHM GMBH (DE) | 2011-12-29 | — | — | US | disclosed |
| US-20110218291-A1 | PROCESS FOR PREPARING AQUEOUS DISPERSIONS | EVONIK ROEHM GMBH (DE) | 2011-09-08 | — | — | US | disclosed |
| US-20080194625-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2008-08-14 | — | — | US | disclosed |
| US-20080132627-A1 | Impact-Resistant Poly(Meth)Acrylate Moulding Masses With High Thermal Stability | ROEHM GMBH (DE) | 2008-06-05 | — | — | US | disclosed |
| US-20060052515-A1 | Process for producing aqueou dispersions | ROEHM GMBH & CO. KG (DE) | 2006-03-09 | — | — | US | disclosed |
| US-20050014786-A1 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2005-01-20 | — | — | US | disclosed |
| US-6590022-B1 | Emulsion polymerization, drying | WACKER-CHEMIE GMBH (DE) | 2003-07-08 | — | — | US | disclosed |
| US-6090868-A | ONE OR MORE ORGANIC POLYMER POWDERS WHICH ARE REDISPERSIBLE IN WATER AND ONE OR MORE ORGANOSILICON POWDERS WHICH ARE REDISPERSIBLE IN WATER ARE ADDED TO THE DRY COATING OR BINDER COMPOSITION. | WACKER-CHEMIE GMBH (DE) | 2000-07-18 | — | — | US | disclosed |
| US-5753733-A | Redispersible, silicon-modified dispersion powder composition, process for its preparation and its use | WACKER-CHEMIE GMBH (DE) | 1998-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014786-A1 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators | CNR2, CNR1, OPRL1 | FNTA 1368/4885FNTB 2071/4885THRB 809/4885 |
| US-20080194625-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CNR2, CNR1, OPRL1 | FNTA 1368/4885FNTB 2071/4885THRB 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.