Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 5/20 | 0.42 |
| ▸ | ECE1 | P42892 | 2/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348683 | 0.85 | MME (0.41) | ACEMMEECE1TGFBR1FOLH1 | |
| SCHEMBL25491158 | 0.85 | ECE1 (0.44) | ACEMMEECE1TGFBR1MMP1 | |
| SCHEMBL13912229 | 0.85 | BIRC2 (0.42) | MMEALDH1A1MMP1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL25209808 | 0.84 | ECE1 (0.43) | ACEMMEECE1TGFBR1MMP1 | |
| Hydrochloric Acid SCHEMBL25209810 | 0.84 | ECE1 (0.43) | ACEMMEECE1TGFBR1MMP1 | |
| Hydrochloric Acid SCHEMBL31285077 | 0.84 | ECE1 (0.43) | ACEMMEECE1TGFBR1MMP1 | |
| SCHEMBL8380947 | 0.82 | MME (0.51) | ACEMMEECE1 | |
| SCHEMBL8380946 | 0.82 | MME (0.51) | ACEMMEECE1 | |
| SCHEMBL31221834 | 0.81 | ECE1 (0.41) | ACEMMEECE1TGFBR1MMP1 | |
| SCHEMBL22043405 | 0.80 | MAPT (0.55) | MMETGFBR1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |