Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 14/20 | 0.39 |
| ▸ | LGMN | Q99538 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.37 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636674 | 0.86 | GAA (0.44) | GAARAD52LGMNTMEM97SIGMAR1 | |
| SCHEMBL6504093 | 0.83 | GAA (0.44) | GAARAD52HRH4LGMNTMEM97 | |
| SCHEMBL6222105 | 0.82 | GAA (0.51) | GAARAD52HRH4LGMNVCP | |
| SCHEMBL2126969 | 0.81 | GAA (0.44) | GAARAD52HRH4LGMNTMEM97 | |
| SCHEMBL6285772 | 0.81 | AKT1 (0.48) | GAARAD52AKT1 | |
| SCHEMBL6220522 | 0.81 | GAA (0.47) | GAARAD52HRH4LGMNVCP | |
| SCHEMBL12324528 | 0.81 | GAA (0.47) | GAARAD52HRH4LGMNUSP28 | |
| SCHEMBL2923335 | 0.81 | GAA (0.38) | GAARAD52HRH4LGMNVCP | |
| Hydrochloric Acid SCHEMBL4627803 | 0.80 | GAA (0.43) | GAARAD52HRH4LGMN | |
| Hydrochloric Acid SCHEMBL4627790 | 0.80 | GAA (0.43) | GAARAD52HRH4LGMN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6923835-B2 | Bis-para-phenylenediamine derivatives comprising a pyrrolidyl group and use of these derivatives for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-08-02 | — | — | US | disclosed |