Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KIF11 | P52732 | 5/20 | 0.53 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | PEPD | P12955 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylurea SCHEMBL54471 | 0.87 | GAA (0.83) | MAPTGAAGFERALDH1A1KIF11 | |
| Phenylurea SCHEMBL27886541 | 0.87 | GAA (0.83) | MAPTGAAGFERALDH1A1KIF11 | |
| Phenylurea SCHEMBL28237284 | 0.87 | GAA (0.83) | MAPTGAAGFERALDH1A1KIF11 | |
| Phenylurea SCHEMBL28147575 | 0.85 | GAA (0.79) | MAPTGAAGFERALDH1A1KIF11 | |
| Phenylurea SCHEMBL6066245 | 0.85 | GAA (0.79) | MAPTGAAGFERALDH1A1KIF11 | |
| Phenylurea SCHEMBL27980768 | 0.85 | GAA (0.79) | MAPTGAAGFERALDH1A1KIF11 | |
| Phenylurea SCHEMBL28620153 | 0.85 | GAA (0.79) | MAPTGAAGFERALDH1A1KIF11 | |
| Phenylurea SCHEMBL28263158 | 0.85 | GAA (0.79) | MAPTGAAGFERALDH1A1KIF11 | |
| Phenylurea SCHEMBL7531144 | 0.85 | GAA (0.79) | MAPTGAAGFERALDH1A1KIF11 | |
| Phenylurea SCHEMBL29800425 | 0.85 | GAA (0.79) | MAPTGAAGFERALDH1A1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051381-A1 | Substituted urea-octatydroindols as antagonists of melanin concentrating hormone receptor 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | claimed |