Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 16/20 | 0.57 |
| ▸ | MEN1 | O00255 | 11/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | TP53 | P04637 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | GFER | P55789 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569283 | 0.84 | — | — | |
| SCHEMBL9547640 | 0.84 | GAA (0.72) | GAAMEN1KMT2AHSD17B10RAB9A | |
| Hydrochloric Acid SCHEMBL8715905 | 0.82 | GAA (0.53) | GAAMEN1KMT2AHSD17B10RAB9A | |
| Ammonia Solution, Strong SCHEMBL1532118 | 0.82 | GAA (0.53) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL4683620 | 0.77 | MEN1 (0.59) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL26115696 | 0.77 | GAA (0.51) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL20323608 | 0.77 | GAA (0.66) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL10852875 | 0.76 | GAA (0.55) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL28723721 | 0.76 | GAA (0.58) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL11968855 | 0.74 | GAA (0.73) | GAAMEN1KMT2AHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |