Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297739 | 1.00 | PTPN2 (0.46) | PTPN2PTPN1PTPN6HPGDEPHX2 | |
| SCHEMBL12440441 | 0.87 | PTPN2 (0.47) | PTPN2PTPN1PTPN6HPGDEPHX2 | |
| SCHEMBL1580316 | 0.81 | HPGD (0.54) | PTPN2PTPN1PTPN6HPGDEPHX2 | |
| SCHEMBL12321126 | 0.78 | HPGD (0.59) | PTPN2PTPN1PTPN6HPGDRECQL | |
| SCHEMBL12440443 | 0.78 | HTT (0.53) | PTPN2PTPN1PTPN6HPGDEPHX2 | |
| SCHEMBL413795 | 0.77 | HPGD (0.55) | PTPN2PTPN1PTPN6HPGDEPHX2 | |
| SCHEMBL18768415 | 0.76 | HPGD (0.57) | PTPN2PTPN1PTPN6HPGDEPHX2 | |
| SCHEMBL9938875 | 0.75 | HPGD (0.56) | PTPN2PTPN1PTPN6HPGDRECQL | |
| SCHEMBL30230001 | 0.75 | MAPT (0.54) | PTPN2PTPN1PTPN6HPGDEPHX2 | |
| SCHEMBL13316252 | 0.74 | EPHX1 (0.44) | PTPN2PTPN1PTPN6HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |