Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.55 |
| ▸ | PPARG | P37231 | 13/20 | 0.55 |
| ▸ | PPARD | Q03181 | 13/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493850 | 0.90 | PPARA (0.50) | PPARAPPARGPPARDMMP1 | |
| SCHEMBL4334772 | 0.88 | PPARA (0.59) | PPARAPPARGPPARDMMP1 | |
| SCHEMBL4335128 | 0.84 | PPARA (0.54) | PPARAPPARGPPARDMMP1 | |
| SCHEMBL6495524 | 0.84 | PPARA (0.76) | PPARAPPARGPPARD | |
| SCHEMBL6497980 | 0.83 | PPARA (0.54) | PPARAPPARGPPARDMMP1 | |
| SCHEMBL6502352 | 0.81 | PPARA (0.79) | PPARAPPARGPPARD | |
| SCHEMBL4336292 | 0.80 | PPARA (0.58) | PPARAPPARGPPARDMMP1 | |
| SCHEMBL4338925 | 0.80 | PPARG (0.55) | PPARAPPARGPPARD | |
| SCHEMBL4341834 | 0.79 | PPARA (0.53) | PPARAPPARGPPARDMMP1 | |
| SCHEMBL6495040 | 0.79 | PPARA (0.62) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |