Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 11/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035559 | 0.86 | LSS (0.58) | LSS | |
| SCHEMBL5035560 | 0.85 | LSS (0.78) | LSS | |
| SCHEMBL5038994 | 0.84 | LSS (0.52) | LSS | |
| SCHEMBL5038562 | 0.84 | LSS (0.55) | LSS | |
| SCHEMBL7167049 | 0.84 | LSS (0.56) | LSS | |
| SCHEMBL5038349 | 0.83 | LSS (0.61) | LSS | |
| SCHEMBL5038924 | 0.82 | LSS (0.56) | LSS | |
| SCHEMBL5038915 | 0.81 | LSS (0.69) | LSS | |
| SCHEMBL5040354 | 0.81 | LSS (0.58) | LSS | |
| SCHEMBL5038931 | 0.80 | LSS (0.52) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951879-B2 | Substituted benzo(b)thiophenes or benzoisothiazoles which inhibit 2,3-oxidosqualene-lanosterol cyclase which is required for the biosynthesis of cholesterol, ergosterol and other sterols | HOFFMANN-LA ROCHE INC. (US) | 2005-10-04 | — | — | US | disclosed |