SCHEMBL6505941

SCHEMBL6505941

CN(C)C(=O)C1(N)CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HPGD P15428 1/20 0.40
EPHX2 P34913 1/20 0.40
RECQL P46063 1/20 0.38
EPHX1 P07099 1/20 0.38
DDB1 Q16531 1/20 0.38
CRBN Q96SW2 1/20 0.38
TSHR P16473 2/20 0.37
ALOX15 P16050 1/20 0.37
ATM Q13315 1/20 0.37
OPRD1 P41143 1/20 0.37
OPRK1 P41145 1/20 0.37
KDM1A O60341 1/20 0.37
GPR119 Q8TDV5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34473285 0.84 USP2 (0.41) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL17848733 0.83 USP2 (0.47) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL849290 0.82 USP2 (0.50) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL1168818 0.82 USP2 (0.50) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL10290907 0.80 USP2 (0.55) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL1692872 0.79 USP2 (0.47) USP2SMN1; SMN2HPGDEPHX2EPHX1
SCHEMBL2800312 0.79 USP2 (0.47) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL182080 0.78 USP2 (0.53) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL6511550 0.78 HPGD (0.43) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL31566597 0.78 USP2 (0.43) USP2SMN1; SMN2HPGDEPHX2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005047253-A1 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD. (KR) 2005-05-26 WO disclosed