Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4890326 | 0.84 | MAPT (0.43) | RAB9ALMNANAMPTMAPTNPSR1 | |
| SCHEMBL8274206 | 0.84 | MAPT (0.43) | RAB9ALMNANAMPTMAPTNPSR1 | |
| SCHEMBL4890329 | 0.84 | MAPT (0.43) | RAB9ALMNANAMPTMAPTNPSR1 | |
| SCHEMBL4064721 | 0.80 | NAMPT (0.39) | RAB9ANAMPTCYP17A1ATR | |
| SCHEMBL4069107 | 0.80 | NAMPT (0.39) | RAB9ANAMPTCYP17A1ATR | |
| SCHEMBL31178934 | 0.79 | HASPIN (0.37) | RAB9ALMNAMAPTNPSR1LATS1 | |
| SCHEMBL14602205 | 0.74 | MAPT (0.62) | RAB9ALMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL13878881 | 0.74 | MAPT (0.62) | RAB9ALMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL22031438 | 0.72 | LATS1 (0.35) | RAB9ALMNANAMPTMAPTLATS1 | |
| SCHEMBL29671146 | 0.72 | LATS1 (0.35) | RAB9ALMNANAMPTMAPTLATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005020987-A1 | HETEROCYCLIC AMIDE DERIVATIVES WHICH POSSES GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2005-03-10 | — | — | WO | disclosed |