Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.68 |
| ▸ | HBB | P68871 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20931739 | 0.85 | KDM4E (0.73) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL29479474 | 0.81 | CYP1A2 (0.54) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL21186232 | 0.81 | KDM4E (0.59) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL14782127 | 0.81 | KDM4E (0.68) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL26227149 | 0.81 | KDM4E (0.68) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL25294746 | 0.81 | CYP1A2 (0.54) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL30354852 | 0.81 | KDM4E (0.68) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL4059342 | 0.80 | KDM4E (0.69) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL31674507 | 0.79 | KDM4E (0.68) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL1002115 | 0.79 | KDM4E (0.68) | KDM4EMEN1KMT2AALDH1A1BRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037839-A1 | NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | ENTOMED (FR) | 2005-04-28 | — | — | WO | disclosed |