Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.61 |
| ▸ | PPARA | Q07869 | 17/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508015 | 1.00 | PPARG (0.61) | PPARGPPARACYP3A4RXRA | |
| SCHEMBL4874828 | 0.81 | PPARG (0.58) | PPARGPPARACYP3A4RXRA | |
| Hydrochloric Acid SCHEMBL5738405 | 0.80 | PPARG (0.57) | PPARGPPARACYP3A4RXRA | |
| SCHEMBL6507507 | 0.79 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL6507504 | 0.79 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL6505630 | 0.79 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL6506097 | 0.79 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL3313236 | 0.79 | PPARG (0.58) | PPARGPPARACYP3A4RXRA | |
| SCHEMBL13742843 | 0.77 | PPARG (0.54) | PPARGPPARACYP3A4RXRA | |
| SCHEMBL5738702 | 0.77 | PPARG (0.65) | PPARGCYP3A4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |