⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24789566 | 0.76 | — | — | |
| SCHEMBL27891915 | 0.76 | S1PR1 (0.32) | — | |
| SCHEMBL24565274 | 0.76 | S1PR1 (0.32) | — | |
| SCHEMBL1584166 | 0.73 | — | — | |
| SCHEMBL16771834 | 0.73 | — | — | |
| SCHEMBL903371 | 0.73 | — | — | |
| SCHEMBL1584163 | 0.73 | — | — | |
| SCHEMBL17098220 | 0.73 | — | — | |
| SCHEMBL17057142 | 0.73 | — | — | |
| SCHEMBL14879791 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | claimed |
| CN-101181188-B | Method for staining cutin fiber and staining reagent box or device | OREAL | 2013-04-03 | — | — | CN | disclosed |
| CN-101091691-B | Keratin fibre dyeing composition containing 2, 3-diamino-6, 7-dihydro-1H, 5H-pyrazolo [1,2-a ] pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and substituted meta-aminophenol | OREAL | 2012-05-02 | — | — | CN | disclosed |
| CN-101181188-A | Method for staining cutin fiber and staining reagent box or device | OREAL (FR) | 2008-05-21 | — | — | CN | disclosed |
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | disclosed |
| CN-1202105-A | 2-alkylpyrrolidines | NOVO NORDISK AS (DK) | 1998-12-16 | — | — | CN | disclosed |