Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 18/20 | 0.94 |
| ▸ | MMP2 | P08253 | 2/20 | 0.65 |
| ▸ | MMP9 | P14780 | 2/20 | 0.65 |
| ▸ | MMP8 | P22894 | 2/20 | 0.65 |
| ▸ | MMP13 | P45452 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6244183 | 0.97 | HPSE (1.00) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6529296 | 0.91 | HPSE (1.00) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6503250 | 0.89 | HPSE (1.00) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL2246214 | 0.88 | HPSE (0.83) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6247649 | 0.88 | HPSE (0.82) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6244234 | 0.87 | HPSE (1.00) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6265143 | 0.87 | HPSE (0.80) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6246003 | 0.86 | HPSE (0.80) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6247745 | 0.86 | HPSE (0.79) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6528428 | 0.85 | HPSE (0.86) | HPSEMMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042495-A1 | (BENZIMIDAZOL-2-YL)-PHENYL-PHENYL-UREA COMPOUNDS AND METHODS FOR INHIBITING HEPARANASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-05-12 | — | — | WO | disclosed |