Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12920289 | 1.00 | HDAC8 (0.37) | HDAC8ICAM1HTR2AHTR2CHTR2B | |
| SCHEMBL653223 | 0.89 | ALB (0.41) | HDAC8ICAM1HTR2AHTR2CHTR2B | |
| SCHEMBL650319 | 0.82 | HDAC8 (0.51) | HDAC8FNTAFNTBTHRBUSP30 | |
| SCHEMBL651669 | 0.82 | HDAC8 (0.51) | HDAC8FNTAFNTBTHRBUSP30 | |
| SCHEMBL652946 | 0.82 | HDAC8 (0.51) | HDAC8FNTAFNTBTHRBUSP30 | |
| SCHEMBL12894279 | 0.80 | HDAC8 (0.39) | HDAC8ICAM1 | |
| SCHEMBL7246422 | 0.75 | HDAC8 (0.46) | HDAC8HTR2AHTR2CHTR2BEPHX2 | |
| SCHEMBL12920276 | 0.73 | FNTA (0.55) | HDAC8FNTAFNTBTHRB | |
| SCHEMBL650724 | 0.73 | FNTA (0.55) | HDAC8FNTAFNTBTHRB | |
| SCHEMBL3283259 | 0.73 | EPHX1 (0.52) | HDAC8KDM4EALDH1A1SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10807925-B2 | Preparation of fluorinated olefins via catalytic dehydrohalogenation of halogenated hydrocarbons | HONEYWELL INTERNATIONAL INC. (US) | 2020-10-20 | — | — | US | claimed |
| US-20150368169-A1 | PREPARATION OF FLUORINATED OLEFINS VIA CATALYTIC DEHYDROHALOGENATION OF HALOGENATED HYDROCARBONS | SOLSTICE ADVANCED MATERIALS US, INC. | 2015-12-24 | — | — | US | claimed |
| US-8648222-B2 | Method for making catalyst compositions of alkali metal halide-doped bivalent metal fluorides and a process for making fluorinated olefins | HONEYWELL INTERNATIONAL INC. (US) | 2014-02-11 | — | — | US | claimed |
| US-8445735-B2 | Conversion of 2-chloro-1,1,1,2-tetrafluoropropane to 2,3,3,3-tetrafluoropropene | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-21 | — | — | US | claimed |
| US-20120232316-A1 | CONVERSION OF 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE TO 2,3,3,3-TETRAFLUOROPROPENE | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-09-13 | — | — | US | claimed |
| EP-2346800-B1 | CONVERSION OF HYDROFLUOROCHLOROPROPANES TO FLUOROPROPENES | DU PONT (US) | 2012-08-29 | — | — | EP | claimed |
| US-20110282111-A1 | Method For Making Catalyst Compositions Of Alkali Metal Halide-Doped Bivalent Metal Fluorides And A Process For Making Fluorinated Olefins | HONEYWELL INTERNATIONAL INC. (US) | 2011-11-17 | — | — | US | claimed |
| EP-2346800-A1 | CONVERSION OF HYDROFLUOROCHLOROPROPANES TO FLUOROPROPENES | E. I. du Pont de Nemours and Company (US) | 2011-07-27 | — | — | EP | claimed |
| US-20110112339-A1 | Dehydrochlorination Of Hydrochlorofluorocarbons Using Pre-Treated Activated Carbon Catalysts | HONEYWELL INTERNATIONAL INC. (US) | 2011-05-12 | — | — | US | claimed |
| US-7884254-B2 | producing a fluorinated alkene by dehydrochlorinating a hydrofluorochloroalkane in the presence of a stabilized demineralized activated carbon wherein hydrochlorofluoroalkane is selected from 1,1,1,2-tetrafluoro-2-chloropropane, for example | HONEYWELL INTERNATIONAL INC. (US) | 2011-02-08 | — | — | US | claimed |
| WO-2010062527-A1 | CONVERSION OF HYDROFLUOROCHLOROPROPANES TO FLUOROPROPENES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-03 | — | — | WO | claimed |
| US-20100105967-A1 | CONVERSION OF 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE TO 2,3,3,3-TETRAFLUOROPROPENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-04-29 | — | — | US | claimed |
| EP-2164824-A1 | PREPARATION OF FLUORINATED OLEFINS VIA CATALYTIC DEHYDROHALOGENATION OF HALOGENATED HYDROCARBONS | Honeywell International Inc. (US) | 2010-03-24 | — | — | EP | claimed |
| US-20090149680-A1 | METHOD FOR MAKING CATALYST COMPOSITIONS OF ALKALI METAL HALIDE-DOPED BIVALENT METAL FLUORIDES AND PROCESS FOR MAKING FLUORINATED OLEFINS | HONEYWELL INTERNATIONAL INC. | 2009-06-11 | — | — | US | claimed |
| US-20090043136-A1 | PREPARATION OF FLUORINATED OLEFINS VIA CATALYTIC DEHYDROHALOGENATION OF HALOGENATED HYDROCARBONS | HONEYWELL INTERNATIONAL, INC. (US) | 2009-02-12 | — | — | US | claimed |
| US-20090043137-A1 | DEHYDROCHLORINATION OF HYDROCHLOROFLUOROCARBONS USING PRE-TREATED ACTIVATED CARBON CATALYSTS | HONEYWELL INTERNATIONAL INC. (US) | 2009-02-12 | — | — | US | claimed |
| WO-2009009421-A1 | PREPARATION OF FLUORINATED OLEFINS VIA CATALYTIC DEHYDROHALOGENATION OF HALOGENATED HYDROCARBONS | HONEYWELL INTERNATIONAL INC. (US) | 2009-01-15 | — | — | WO | claimed |
| US-10807925-B2 | Preparation of fluorinated olefins via catalytic dehydrohalogenation of halogenated hydrocarbons | HONEYWELL INTERNATIONAL INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-20080194625-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2008-08-14 | — | — | US | disclosed |
| US-20050014786-A1 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014786-A1 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators | CNR2, CNR1, OPRL1 | HDAC8 2618/4885ICAM1 3936/4885HTR2A 32/4885 |
| US-20080194625-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CNR2, CNR1, OPRL1 | HDAC8 2618/4885ICAM1 3936/4885HTR2A 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.