Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30853137 | 0.86 | HPGD (0.51) | EPHX1HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL3254458 | 0.84 | EPHX1 (0.54) | EPHX1HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL31566747 | 0.84 | HPGD (0.42) | EPHX1HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL23439145 | 0.82 | EPHX1 (0.51) | EPHX1HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL3321642 | 0.82 | EPHX1 (0.49) | EPHX1HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL4609802 | 0.81 | EPHX1 (0.51) | EPHX1HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL6132692 | 0.81 | EPHX1 (0.51) | EPHX1HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL3122325 | 0.80 | EPHX1 (0.50) | EPHX1HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL6510036 | 0.80 | EPHX1 (0.50) | EPHX1HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL5887760 | 0.80 | EPHX1 (0.50) | EPHX1HPGDUSP2SMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411940-B1 | BRIDGED PIPERIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS | MERCK & CO INC (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2005047253-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |