SCHEMBL6507358

SCHEMBL6507358

Clc1ccc(OC2C[C@H]3CC[C@@H](C2)N3)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 17/20 1.00
SLC6A2 P23975 13/20 1.00
SLC6A3 Q01959 13/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5316218 1.00 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3
SCHEMBL14410807 1.00 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3
SCHEMBL911551 0.93 SLC6A4 (0.87) SLC6A4SLC6A2SLC6A3
SCHEMBL911388 0.93 SLC6A4 (0.87) SLC6A4SLC6A2SLC6A3
SCHEMBL911387 0.93 SLC6A4 (0.87) SLC6A4SLC6A2SLC6A3
Trifluoroacetic Acid SCHEMBL20958538 0.85 SLC6A4 (0.73) SLC6A4SLC6A2SLC6A3
SCHEMBL23159342 0.81 SLC6A4 (0.71) SLC6A4SLC6A2SLC6A3
SCHEMBL6155913 0.81 SLC6A4 (0.69) SLC6A4SLC6A2SLC6A3
SCHEMBL16292368 0.81 SLC6A4 (0.69) SLC6A4SLC6A2SLC6A3
SCHEMBL5446376 0.81 SLC6A4 (0.69) SLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005014578-A1 PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS GLAXO GROUP LIMITED (GB) 2005-02-17 WO disclosed