Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 13/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507567 | 1.00 | PIK3CG (0.49) | PIK3CGHPGDPIM1PIM3PIM2 | |
| SCHEMBL6510852 | 0.84 | MGAM (0.50) | PIK3CGHPGDPIM1PIM3PIM2 | |
| SCHEMBL6510848 | 0.84 | MGAM (0.50) | PIK3CGHPGDPIM1PIM3PIM2 | |
| SCHEMBL6533265 | 0.83 | PTAFR (0.46) | GAA | |
| SCHEMBL6507599 | 0.82 | GSK3B (0.48) | HPGDPIM1PIM3PIM2GSK3B | |
| SCHEMBL6507602 | 0.82 | GSK3B (0.48) | HPGDPIM1PIM3PIM2GSK3B | |
| SCHEMBL6511845 | 0.81 | PIM1 (0.50) | HPGDPIM1PIM3PIM2GSK3B | |
| SCHEMBL6511842 | 0.81 | PIM1 (0.50) | HPGDPIM1PIM3PIM2GSK3B | |
| SCHEMBL6512061 | 0.81 | PIM1 (0.45) | HPGDPIM1PIM3PIM2MGAM | |
| SCHEMBL6512065 | 0.81 | PIM1 (0.45) | HPGDPIM1PIM3PIM2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | claimed |
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |