Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201146 | 0.82 | NR1H2 (0.37) | HSD17B10USP2SMN1; SMN2HPGDCHRM2 | |
| SCHEMBL201144 | 0.82 | NR1H2 (0.37) | HSD17B10USP2SMN1; SMN2HPGDCHRM2 | |
| SCHEMBL201569 | 0.82 | NR1H2 (0.37) | HSD17B10USP2SMN1; SMN2HPGDCHRM2 | |
| SCHEMBL16790938 | 0.79 | USP2 (0.38) | HSD17B10USP2SMN1; SMN2HPGDCHRM2 | |
| SCHEMBL200833 | 0.79 | ACE (0.48) | HSD17B10USP2SMN1; SMN2HPGDCHRM2 | |
| SCHEMBL17031886 | 0.79 | USP2 (0.38) | HSD17B10USP2SMN1; SMN2HPGDCHRM2 | |
| SCHEMBL200834 | 0.79 | ACE (0.48) | HSD17B10USP2SMN1; SMN2HPGDCHRM2 | |
| SCHEMBL201910 | 0.79 | ACE (0.48) | HSD17B10USP2SMN1; SMN2HPGDCHRM2 | |
| SCHEMBL6904285 | 0.78 | HSD17B10 (0.36) | HSD17B10SMN1; SMN2USP30UCHL1PREP | |
| SCHEMBL6904287 | 0.78 | HSD17B10 (0.36) | HSD17B10SMN1; SMN2USP30UCHL1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |