Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN3B | O60391 | 9/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 9/20 | 0.49 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | FLT1 | P17948 | 3/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862230 | 0.86 | GRIN3B (0.64) | GRIN3BGRIN1GRIN2CKDRFLT1 | |
| SCHEMBL22859701 | 0.82 | GRIN3B (0.61) | GRIN3BGRIN1GRIN2CKDRFLT1 | |
| SCHEMBL22859518 | 0.79 | GRIN3B (0.65) | GRIN3BGRIN1GRIN2CKDRFLT1 | |
| SCHEMBL22859648 | 0.75 | GRIN3B (0.62) | GRIN3BGRIN1GRIN2CKDRFLT1 | |
| SCHEMBL22862186 | 0.75 | GRIN3B (0.62) | GRIN3BGRIN1GRIN2CKDRFLT1 | |
| SCHEMBL22859470 | 0.74 | GRIN3B (0.59) | GRIN3BGRIN1GRIN2CKDRFLT1 | |
| SCHEMBL29368421 | 0.74 | GRIN3B (0.59) | GRIN3BGRIN1GRIN2CKDRFLT1 | |
| SCHEMBL22859682 | 0.74 | GRIN3B (0.59) | GRIN3BGRIN1GRIN2CKDRFLT1 | |
| SCHEMBL199636 | 0.74 | DAO (0.46) | GRIN3BGRIN1GRIN2CKDRFLT1 | |
| SCHEMBL29998454 | 0.74 | DAO (0.46) | GRIN3BGRIN1GRIN2CKDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081960-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |