Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL649105 | 1.00 | DPP4 (0.55) | DPP4DPP9DPP8EPHX2 | |
| SCHEMBL647780 | 0.94 | DPP4 (0.55) | DPP4DPP9DPP8EPHX2 | |
| SCHEMBL648583 | 0.92 | DPP4 (0.53) | DPP4DPP9DPP8EPHX2 | |
| SCHEMBL4756036 | 0.92 | DPP4 (0.53) | DPP4DPP9DPP8EPHX2 | |
| SCHEMBL5479049 | 0.89 | DPP4 (0.42) | DPP4DPP9DPP8EPHX2 | |
| SCHEMBL647393 | 0.86 | DPP4 (0.58) | DPP4DPP9DPP8EPHX2 | |
| SCHEMBL647580 | 0.86 | DPP4 (0.53) | DPP4DPP9DPP8EPHX2 | |
| SCHEMBL647803 | 0.85 | DPP4 (0.55) | DPP4DPP9DPP8EPHX2 | |
| SCHEMBL648116 | 0.83 | DPP4 (0.62) | DPP4DPP9DPP8EPHX2 | |
| SCHEMBL647636 | 0.83 | DPP4 (0.62) | DPP4DPP9DPP8EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215784-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBVIE INC. | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215784-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | DPP4, DPP3, DPP7 | DPP4 1/4885DPP9 4/4885DPP8 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.