SCHEMBL6507960

SCHEMBL6507960

CCC[Si](CCC)(CCC)OCCc1cc(F)cc(F)c1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.34
CYP17A1 P05093 1/20 0.30
CYP21A2 P08686 1/20 0.30
CYP11B1 P15538 1/20 0.30
DAO P14920 1/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6509728 0.78
SCHEMBL15736493 0.75 IDO1 (0.34) IDO1CYP17A1CYP21A2CYP11B1DAO
SCHEMBL15734702 0.73 IDO1 (0.35) IDO1CYP17A1CYP21A2CYP11B1DAO
SCHEMBL5145598 0.73 IDO1 (0.35) IDO1CYP17A1CYP21A2CYP11B1DAO
SCHEMBL6503741 0.73 KDR (0.30)
SCHEMBL15738645 0.72 TRPV1 (0.34) IDO1TRPV1
SCHEMBL12078265 0.71 IDO1 (0.38) IDO1CYP17A1CYP21A2CYP11B1DAO
SCHEMBL15736145 0.71 TRPV1 (0.36) IDO1TRPV1
SCHEMBL294824 0.71 IDO1 (0.42) IDO1CYP17A1CYP21A2CYP11B1DAO
SCHEMBL15734312 0.70 IDO1 (0.36) IDO1CYP17A1CYP21A2CYP11B1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005108374-A1 INSECTICIDAL DIAZOLE AND TRIAZOLE DERIVATIVES FMC CORPORATION (US) 2005-11-17 WO disclosed