Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838771 | 0.94 | KMT2A (0.65) | MEN1KMT2ALMNAPOLBTP53 | |
| SCHEMBL25124077 | 0.93 | MEN1 (0.60) | MEN1KMT2ALMNAPOLBTP53 | |
| SCHEMBL583477 | 0.92 | KMT2A (0.63) | MEN1KMT2ALMNAPOLBTP53 | |
| SCHEMBL28666392 | 0.92 | KMT2A (0.63) | MEN1KMT2ALMNAPOLBTP53 | |
| SCHEMBL582556 | 0.92 | KMT2A (0.63) | MEN1KMT2ALMNAPOLBTP53 | |
| SCHEMBL29418129 | 0.92 | TP53 (0.69) | MEN1KMT2ALMNAPOLBTP53 | |
| SCHEMBL159005 | 0.92 | TP53 (0.69) | MEN1KMT2ALMNAPOLBTP53 | |
| SCHEMBL13740267 | 0.90 | TP53 (0.71) | MEN1KMT2ALMNAPOLBTP53 | |
| SCHEMBL15522001 | 0.90 | TP53 (0.71) | MEN1KMT2ALMNAPOLBTP53 | |
| SCHEMBL9857798 | 0.88 | TP53 (0.65) | MEN1KMT2ALMNAPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | MEN1 4860/4885KMT2A 2887/4885LMNA 3747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.