Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553801 | 0.77 | GRIN2D (0.52) | KDM4EATMKDM1AGRIN2DGRIN3B | |
| SCHEMBL6553794 | 0.77 | GRIN2D (0.52) | KDM4EATMKDM1AGRIN2DGRIN3B | |
| SCHEMBL6281310 | 0.76 | NPSR1 (0.46) | KDM4EATMHCAR2 | |
| SCHEMBL6279268 | 0.76 | NPSR1 (0.46) | KDM4EATMHCAR2 | |
| SCHEMBL15475612 | 0.74 | TSHR (0.41) | KDM4EATMHCAR2 | |
| SCHEMBL6279256 | 0.74 | TSHR (0.41) | KDM4EATMHCAR2 | |
| SCHEMBL6803983 | 0.74 | TSHR (0.41) | KDM4EATMHCAR2 | |
| SCHEMBL11172053 | 0.72 | KDM4E (0.39) | KDM4EATMKDM1AGRIN2DGRIN3B | |
| SCHEMBL11172103 | 0.72 | KDM4E (0.39) | KDM4EATMKDM1AGRIN2DGRIN3B | |
| SCHEMBL11172080 | 0.72 | KDM4E (0.39) | KDM4EATMKDM1AGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042509-A1 | 7-`(7-ALKOXY)-CHROM-3-EN-6-YL!-HEPTATRIENOIC ACID AND 7-`(3ALKOXY)-5,6-DIHYDRONAPHTHALEN-2-YL!-HEPTATRIENOIC ACID DERIVATIVES MODULATORS | ALLERGAN, INC. (US) | 2005-05-12 | — | — | WO | disclosed |