Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | TPMT | P51580 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372638 | 0.94 | KMT2A (0.64) | HTTHDAC6RAB9AMEN1KMT2A | |
| SCHEMBL6508777 | 0.86 | MAPT (0.60) | HTTHDAC6RAB9AMEN1KMT2A | |
| Vanillic Acid SCHEMBL26179 | 0.86 | HTT (1.00) | HTTHDAC6RAB9AMEN1KMT2A | |
| Vanillic Acid SCHEMBL9711598 | 0.86 | HTT (1.00) | HTTHDAC6RAB9AMEN1KMT2A | |
| Vanillic Acid SCHEMBL29378740 | 0.86 | HTT (1.00) | HTTHDAC6RAB9AMEN1KMT2A | |
| Vanillic Acid SCHEMBL18334646 | 0.84 | HTT (0.96) | HTTHDAC6RAB9AMEN1KMT2A | |
| Vanillic Acid SCHEMBL17443329 | 0.84 | HTT (0.96) | HTTHDAC6RAB9AMEN1KMT2A | |
| Vanillic Acid SCHEMBL31265874 | 0.84 | HTT (0.96) | HTTHDAC6RAB9AMEN1KMT2A | |
| Vanillic Acid SCHEMBL6697041 | 0.84 | HTT (0.96) | HTTHDAC6RAB9AMEN1KMT2A | |
| Vanillic Acid SCHEMBL8853983 | 0.84 | HTT (0.96) | HTTHDAC6RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023762-A1 | PYRROLIDINE-2-CARBONITRILE DERIVATIVES AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2005-03-17 | — | — | WO | disclosed |