Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.82 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PRNP | P04156 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11978723 | 0.92 | KMT2A (0.72) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL28233640 | 0.92 | KMT2A (0.72) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL4897772 | 0.86 | MEN1 (0.69) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL4901594 | 0.86 | MEN1 (0.69) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL15460380 | 0.85 | MEN1 (0.63) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL17051577 | 0.84 | MEN1 (0.61) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL17051603 | 0.84 | MEN1 (0.61) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL2666244 | 0.83 | MEN1 (0.59) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL10194257 | 0.83 | KDM4E (0.62) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL9486988 | 0.81 | KMT2A (0.60) | MEN1KMT2ANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542978-A1 | NOVEL BIO-ACTIVE MOLECULES | Orchid Chemicals and Pharmaceuticals Ltd (IN) | 2005-06-22 | — | — | EP | claimed |
| WO-2004009560-A1 | NOVEL BIO-ACTIVE MOLECULES | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2004-01-29 | — | — | WO | claimed |
| CN-102574813-A | Cyclic azine derivatives, process for producing the same, and organic electroluminescent element containing the same as constituent | TOSOH CORP | 2012-07-11 | — | — | CN | disclosed |