Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648355 | 1.00 | DPP4 (0.49) | DPP4DPP9 | |
| SCHEMBL6201221 | 1.00 | DPP4 (0.49) | DPP4DPP9 | |
| SCHEMBL648406 | 0.89 | DPP4 (0.47) | DPP4 | |
| SCHEMBL1377902 | 0.89 | DPP4 (0.47) | DPP4 | |
| SCHEMBL648878 | 0.89 | DPP4 (0.47) | DPP4 | |
| SCHEMBL645803 | 0.89 | DPP4 (0.54) | DPP4DPP9 | |
| SCHEMBL1376692 | 0.89 | DPP4 (0.54) | DPP4DPP9 | |
| SCHEMBL646036 | 0.87 | DPP4 (0.45) | DPP4 | |
| SCHEMBL1378114 | 0.86 | DPP4 (0.54) | DPP4DPP9 | |
| SCHEMBL1376855 | 0.84 | DPP4 (0.44) | DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215784-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBVIE INC. | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215784-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | DPP4, DPP3, DPP7 | DPP4 1/4885DPP9 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.