Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | PREP | P48147 | 2/20 | 0.67 |
| ▸ | FAP | Q12884 | 2/20 | 0.67 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.67 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.67 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367821 | 1.00 | DPP4 (1.00) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL5373399 | 1.00 | DPP4 (1.00) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL5373403 | 1.00 | DPP4 (1.00) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL6509054 | 1.00 | DPP4 (1.00) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL5367816 | 1.00 | DPP4 (1.00) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL5419214 | 0.90 | DPP4 (0.85) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL5419219 | 0.90 | DPP4 (0.85) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL5381327 | 0.85 | DPP4 (0.83) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL5376046 | 0.84 | DPP4 (0.79) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL5364250 | 0.83 | DPP4 (0.80) | DPP4PREPFAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023762-A1 | PYRROLIDINE-2-CARBONITRILE DERIVATIVES AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2005-03-17 | — | — | WO | disclosed |