Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21300545 | 0.80 | CA1 (0.38) | CA1CA2CA12 | |
| SCHEMBL26553249 | 0.79 | CYP2D6 (0.32) | CA1CA2CA12CA9 | |
| SCHEMBL10486711 | 0.78 | PARG (0.38) | PARGCA1CA2TP53CA12 | |
| SCHEMBL1754136 | 0.76 | PARG (0.37) | PARGCA2TP53 | |
| SCHEMBL7588318 | 0.76 | CA1 (0.37) | CA1CA2CA12CA9 | |
| SCHEMBL1727841 | 0.74 | TP53 (0.36) | PARGTP53 | |
| SCHEMBL18938259 | 0.72 | CA1 (0.35) | CA1CA2 | |
| SCHEMBL42072 | 0.71 | — | — | |
| SCHEMBL18595757 | 0.70 | GRIA1 (0.38) | PARG | |
| SCHEMBL19035634 | 0.69 | TSHR (0.33) | PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005026136-A2 | 2, 2'-AZINO-BIS-THIAZOLINES AND USES THEREOF AS AIR- AND WATER- STABLE RADICAL PRECURSORS | ARMAND MICHEL (FR) | 2005-03-24 | — | — | WO | disclosed |