Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516793 | 0.87 | PTGDR2 (0.54) | PTGDR2CYP2C9AKR1B1SLC6A4 | |
| SCHEMBL6509710 | 0.86 | PTGDR2 (0.70) | PTGDR2CYP2C9AKR1B1SLC6A4 | |
| SCHEMBL1406030 | 0.83 | PTGDR2 (1.00) | PTGDR2CYP2C9AKR1B1SLC6A4 | |
| SCHEMBL15016509 | 0.83 | PTGDR2 (0.78) | PTGDR2CYP2C9AKR1B1SLC6A4 | |
| SCHEMBL1406050 | 0.81 | PTGDR2 (1.00) | PTGDR2CYP2C9AKR1B1 | |
| SCHEMBL1406083 | 0.81 | PTGDR2 (1.00) | PTGDR2CYP2C9AKR1B1SLC6A4 | |
| SCHEMBL4903988 | 0.80 | PTGDR2 (1.00) | PTGDR2CYP2C9AKR1B1SLC6A4 | |
| SCHEMBL1406139 | 0.80 | PTGDR2 (0.83) | PTGDR2CYP2C9AKR1B1SLC6A4 | |
| SCHEMBL3006606 | 0.80 | PTGDR2 (1.00) | PTGDR2CYP2C9AKR1B1 | |
| SCHEMBL1406107 | 0.80 | PTGDR2 (0.83) | PTGDR2CYP2C9AKR1B1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121141-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE THEREOF FOR TREATING DISEASES MEDIATED BY PROSTAGLANDIN D2 (PGD2) | OXAGEN LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |