Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.57 |
| ▸ | PPARG | P37231 | 7/20 | 0.57 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3286634 | 1.00 | PPARA (0.57) | PPARAPPARGTLR7PPARDGRM2 | |
| SCHEMBL3286633 | 0.98 | PPARA (0.56) | PPARAPPARGTLR7PPARDGRM2 | |
| SCHEMBL3285323 | 0.98 | PPARA (0.56) | PPARAPPARGTLR7PPARDGRM2 | |
| SCHEMBL3285148 | 0.94 | PPARA (0.62) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6511450 | 0.93 | PPARA (0.61) | PPARAPPARGTLR7PPARD | |
| SCHEMBL3286811 | 0.93 | PPARA (0.62) | PPARAPPARGTLR7PPARD | |
| SCHEMBL3844826 | 0.92 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL3284481 | 0.91 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL3287505 | 0.91 | PPARA (0.55) | PPARAPPARGTLR7PPARDGRM2 | |
| SCHEMBL6513058 | 0.91 | PPARA (0.60) | PPARAPPARGTLR7PPARDGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | disclosed |