Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.57 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.57 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.57 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | ADK | P55263 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287236 | 0.85 | NISCH (0.64) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL14886257 | 0.83 | NISCH (0.61) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL10463757 | 0.82 | CSNK1A1 (0.46) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL26259955 | 0.79 | NISCH (0.61) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL2095606 | 0.78 | NISCH (0.55) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL26259965 | 0.77 | NISCH (0.54) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL16058907 | 0.77 | CSNK1A1 (0.43) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL1458606 | 0.76 | NISCH (0.53) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL1369295 | 0.76 | NISCH (0.53) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL471923 | 0.76 | NISCH (0.70) | CSNK1A1TYRO3DYRK1BNISCHMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063759-A1 | PROCESS FOR PREPARING PYRROLO[2, 1-c] [1, 4] BENZODIAZEPINE HYBRIDS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | disclosed |
| US-4794113-A | ANTICHOLESTEROL, ANTILIPEMIC, ANTICOAGULANT | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-12-27 | — | — | US | disclosed |
| US-4794113-A | ANTICHOLESTEROL, ANTILIPEMIC, ANTICOAGULANT | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-12-27 | — | — | US | disclosed |