Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.62 |
| ▸ | PPARG | P37231 | 7/20 | 0.62 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511563 | 1.00 | PPARA (0.62) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6510004 | 1.00 | PPARA (0.62) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6510857 | 1.00 | PPARA (0.62) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6512670 | 1.00 | PPARA (0.62) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6519119 | 0.93 | PPARA (0.52) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6509754 | 0.92 | PPARA (0.51) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6511113 | 0.92 | PPARA (0.51) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6511892 | 0.90 | PPARA (0.52) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6511817 | 0.89 | PPARA (0.62) | PPARAPPARGTLR7PPARD | |
| SCHEMBL6516926 | 0.89 | PPARA (0.62) | PPARAPPARGTLR7PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | claimed |
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | disclosed |