SCHEMBL650988

SCHEMBL650988

C#CC(=O)[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13259198 0.71
SCHEMBL429486 0.67
SCHEMBL10306576 0.62
SCHEMBL212389 0.62
SCHEMBL31024017 0.61
SCHEMBL3134256 0.60
SCHEMBL3254153 0.60
SCHEMBL28759027 0.60
SCHEMBL14760120 0.58
Propiolic Acid SCHEMBL5148173 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8325273-A None JP disclosed
JP-9100285-A None JP disclosed
US-10287225-B2 Chain multiyne compound, preparation method and application thereof XIAMEN UNIVERSITY (CN) 2019-05-14 US disclosed
CN-108350574-A COLD SINTERING OF SOLID PRECURSORS 恩特格里斯公司 2018-07-31 CN disclosed
US-20180065908-A1 CHAIN MULTIYNE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF XIAMEN UNIVERSITY (CN) 2018-03-08 US disclosed
US-8431117-B2 Sickled erythrocytes with anti-tumor agents induce tumor vaso-occlusion and tumoricidal effects TERMAN DAVID S (US) 2013-04-30 US disclosed
US-20120195869-A1 Sickled Erythrocytes with Anti-tumor Agents Induce Tumor Vaso-occlusion and Tumoricidal Effects TERMAN DAVID S (US) 2012-08-02 US disclosed
US-8119826-B2 Process for the preparation of beta-santalol and derivatives thereof FIRMENICH SA (CH) 2012-02-21 US disclosed
EP-2386537-A2 Intermediates for the preparation of beta-santalol and derivatives thereof FIRMENICH SA (CH) 2011-11-16 EP disclosed
US-20110254473-A1 ARRANGEMENT AND METHOD FOR CONTROLLING FREQUENCY CONVERTER MODULES ABB OY (FI) 2011-10-20 US disclosed
WO-2002104072-A2 EMISSIVE MULTICHROMOPHORIC SYSTEMS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2002-12-27 WO disclosed
US-6051569-A 1'S, 5R, 6R-carbapenem derivatives and antimicrobial agents comprising the same SUNTORY LIMITED (JP) 2000-04-18 US disclosed
EP-0826687-A1 Carbapenem derivatives and antimicrobial agents comprising the same SUNTORY LIMITED (JP) 1998-03-04 EP disclosed
JP-H09100285-A PRODUCTION OF OPTICALLY ACTIVE 5-HYDROXY-3-OXO-6-HEPTYNOIC ACID ESTER DERIVATIVE UBE IND LTD 1997-04-15 JP disclosed
JP-H08325273-A PRODUCTION OF TRIMETHYLSILYLPROPYNAL SHIN ETSU CHEM CO LTD 1996-12-10 JP disclosed
EP-0171064-B1 Azetidinone derivative and processes for production thereof FUJISAWA PHARMACEUTICAL CO (JP) 1995-07-12 EP disclosed
US-4845210-A Azetidinone derivatives and processes for production thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-07-04 US disclosed
EP-0171064-A1 Azetidinone derivative and processes for production thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-02-12 EP disclosed
US-4444771-A Azeto triazolo pyrazine β-lactam antibacterial agents BEECHAM GROUP LIMITED (GB) 1984-04-24 US disclosed
EP-0048096-A1 Beta-lactam antibacterial agents BEECHAM GROUP PLC (GB) 1982-03-24 EP disclosed