SCHEMBL6509890

SCHEMBL6509890

Cc1nnc(C(=O)C2CCCN2C(=O)CNC23CC4CC(CC(O)(C4)C2)C3)o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 19/20 1.00
DPP7 Q9UHL4 9/20 1.00
DPP8 Q6V1X1 8/20 1.00
FAP Q12884 3/20 0.55
DPP9 Q86TI2 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6511786 0.85 DPP4 (0.83) DPP4DPP7DPP8FAPDPP9
SCHEMBL6507564 0.85 DPP4 (0.73) DPP4DPP7DPP8FAPDPP9
SCHEMBL17048339 0.82 DPP4 (0.69) DPP4DPP7DPP8FAPDPP9
SCHEMBL17048338 0.82 DPP4 (0.69) DPP4DPP7DPP8FAPDPP9
SCHEMBL17048286 0.82 DPP4 (0.69) DPP4DPP7DPP8FAPDPP9
SCHEMBL6530052 0.79 DPP4 (0.79) DPP4DPP7DPP8FAPDPP9
SCHEMBL12354534 0.78 DPP4 (0.69) DPP4DPP7DPP8FAPDPP9
SCHEMBL15855961 0.78 DPP4 (0.69) DPP4DPP7DPP8FAPDPP9
SCHEMBL6530580 0.76 DPP4 (0.82) DPP4DPP7DPP8DPP9
SCHEMBL7795161 0.76 DPP4 (0.71) DPP4DPP7DPP8FAPDPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005037828-A1 NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT LG LIFE SCIENCES LTD. (KR) 2005-04-28 WO disclosed