Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722740 | 0.86 | USP2 (0.49) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL6531219 | 0.85 | HPGD (0.47) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL6506874 | 0.84 | HPGD (0.46) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL15487763 | 0.83 | HSD17B10 (0.48) | HPGDUSP2SMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL6511550 | 0.82 | HPGD (0.43) | HPGDUSP2SMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL15491798 | 0.81 | HPGD (0.51) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL3327975 | 0.80 | HPGD (0.49) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL6508625 | 0.79 | HPGD (0.49) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL18097955 | 0.78 | HPGD (0.71) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL18432213 | 0.78 | HPGD (0.71) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047253-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |