Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.63 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.63 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.63 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 2/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514688 | 0.97 | DPP4 (0.64) | DPP4DPP8DPP7DPP9PKM | |
| SCHEMBL6530464 | 0.91 | DPP4 (0.77) | DPP4DPP8DPP7PKMCPT1A | |
| SCHEMBL6530982 | 0.89 | DPP4 (0.63) | DPP4DPP8DPP7PKMCPT1A | |
| SCHEMBL6528164 | 0.88 | DPP4 (0.78) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL6532456 | 0.86 | DPP4 (0.64) | DPP4DPP8DPP7DPP9PKM | |
| SCHEMBL6533584 | 0.86 | DPP4 (0.82) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL6529453 | 0.85 | DPP4 (0.58) | DPP4DPP8DPP7PKMCPT1A | |
| SCHEMBL6527703 | 0.82 | DPP4 (0.59) | DPP4DPP8DPP7DPP9PKM | |
| SCHEMBL6528023 | 0.82 | DPP4 (0.54) | DPP4DPP8DPP7CPT1ACPT2 | |
| SCHEMBL6510648 | 0.82 | DPP4 (0.61) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |