Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510268 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1PKMMAOBMAOA | |
| SCHEMBL2764237 | 0.95 | KDM4E (0.61) | KDM4EALDH1A1PKMMAOBMAOA | |
| SCHEMBL9475742 | 0.89 | KDM4E (0.60) | KDM4EALDH1A1PKMMAOBMAOA | |
| SCHEMBL9475746 | 0.89 | KDM4E (0.60) | KDM4EALDH1A1PKMMAOBMAOA | |
| SCHEMBL5377337 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1PKMMAOBMAOA | |
| SCHEMBL5377339 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1PKMMAOBMAOA | |
| SCHEMBL13243557 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1PKMMAOBMAOA | |
| SCHEMBL2999434 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1PKMMAOBMAOA | |
| SCHEMBL2999433 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1PKMMAOBMAOA | |
| SCHEMBL3967800 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1PKMMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |