Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11198740 | 0.97 | TSHR (0.53) | TSHRTDP1FFAR3LCKFYN | |
| Bicarbonate SCHEMBL27668414 | 0.89 | TSHR (0.61) | TSHRTDP1FFAR3LCKFYN | |
| Acetone SCHEMBL27912055 | 0.89 | TSHR (0.61) | TSHRTDP1FFAR3LCKFYN | |
| Oxalic Acid SCHEMBL27320483 | 0.86 | TSHR (0.57) | TSHRTDP1FFAR3LCKFYN | |
| Hydrogen Peroxide SCHEMBL2635895 | 0.84 | TSHR (0.80) | TSHRTDP1ALDH1A1HSD17B10 | |
| Pivalate SCHEMBL300936 | 0.83 | TSHR (0.53) | TSHRTDP1ALDH1A1HSD17B10DGAT1 | |
| Methacrylic Acid SCHEMBL16007806 | 0.82 | TDP1 (0.44) | TSHRTDP1FFAR3LCKFYN | |
| SCHEMBL28283124 | 0.81 | TSHR (0.73) | TSHRTDP1ALDH1A1 | |
| Acetic Acid SCHEMBL11198741 | 0.80 | TSHR (0.50) | TSHRTDP1ALDH1A1HSD17B10 | |
| Acetic Acid SCHEMBL25274821 | 0.80 | HMGCR (0.42) | TSHRTDP1FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197677-A1 | Two-Part Curable Adhesive Composition | HENKEL AG & CO KGAA (DE) | 2025-06-19 | — | — | US | claimed |
| WO-2024050683-A1 | TWO-PART CURABLE ADHESIVE COMPOSITION | HENKEL AG & CO. KGAA (DE) | 2024-03-14 | — | — | WO | claimed |
| US-6920901-B2 | Heat resistant fuel hose | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2005-07-26 | — | — | US | claimed |
| US-6867263-B2 | Method of vulcanized bonding of heat-resistant rubber | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2005-03-15 | — | — | US | claimed |
| US-20030188793-A1 | Heat resistant fuel hose | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2003-10-09 | — | — | US | claimed |
| US-20030187146-A1 | Method of vulcanized bonding of heat-resistant rubber | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2003-10-02 | — | — | US | claimed |
| EP-4665573-A1 | METHOD FOR ENCAPSULATING ELECTRICAL CELLS BEARING A NICKEL-BASED SURFACE | Huntsman Advanced Materials (Switzerland) GmbH (CH) | 2025-12-24 | — | — | EP | disclosed |
| US-20250197677-A1 | Two-Part Curable Adhesive Composition | HENKEL AG & CO KGAA (DE) | 2025-06-19 | — | — | US | disclosed |
| CN-119836457-A | Two-component curable adhesive composition | 汉高股份有限及两合公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119432064-A | High-impact-resistance high-toughness bio-based nylon composite material and preparation method thereof | 中国科学院宁波材料技术与工程研究所 | 2025-02-14 | — | — | CN | disclosed |
| US-20240336815-A1 | FOAMED ACRYLIC POLYMER PRIMERLESS ADHESIVE | ILLINOIS TOOL WORKS INC. (US) | 2024-10-10 | — | — | US | disclosed |
| WO-2024170393-A1 | METHOD FOR ENCAPSULATING ELECTRICAL CELLS BEARING A NICKEL-BASED SURFACE | HUNTSMAN ADVANCED MATERIALS LICENSING (SWITZERLAND) GMBH (CH) | 2024-08-22 | — | — | WO | disclosed |
| WO-2024050683-A1 | TWO-PART CURABLE ADHESIVE COMPOSITION | HENKEL AG & CO. KGAA (DE) | 2024-03-14 | — | — | WO | disclosed |
| US-20050068593-A1 | Holographic optical recording medium, manufacturing method thereof and holographic optical recording method | KABUSHIKI KAISHA TOSHIBA | 2005-03-31 | — | — | US | disclosed |
| US-6867263-B2 | Method of vulcanized bonding of heat-resistant rubber | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| EP-1359183-A1 | Method of vulcanized bonding of heat-resistant rubber | Tokai Rubber Industries, Ltd. (JP) | 2003-11-05 | — | — | EP | disclosed |
| US-20030188793-A1 | Heat resistant fuel hose | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2003-10-09 | — | — | US | disclosed |
| US-20030187146-A1 | Method of vulcanized bonding of heat-resistant rubber | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1348538-A1 | Heat resistant fuel hose | Tokai Rubber Industries, Ltd. (JP) | 2003-10-01 | — | — | EP | disclosed |
| US-6375872-B1 | Microencapsulated adhesive | MOORE BUSINESS FORMS | 2002-04-23 | — | — | US | disclosed |