SCHEMBL6511137

SCHEMBL6511137

CC(C)Oc1c(CCCO)cc2c(c1Cl)OC(C)(C)C=C2C(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6512345 0.93 PPARG (0.31) PPARGPPARA
SCHEMBL6280568 0.78 PPARG (0.30) PPARGPPARA
SCHEMBL6279556 0.78
SCHEMBL6278322 0.77 PPARG (0.33) PPARGPPARA
SCHEMBL6281214 0.77 PPARG (0.30) PPARGPPARA
SCHEMBL6283086 0.76 PPARG (0.33) PPARGPPARA
SCHEMBL6279928 0.76
SCHEMBL6275498 0.75
SCHEMBL6283869 0.74
SCHEMBL6283864 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005042509-A1 7-`(7-ALKOXY)-CHROM-3-EN-6-YL!-HEPTATRIENOIC ACID AND 7-`(3­ALKOXY)-5,6-DIHYDRONAPHTHALEN-2-YL!-HEPTATRIENOIC ACID DERIVATIVES MODULATORS ALLERGAN, INC. (US) 2005-05-12 WO disclosed