Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 14/20 | 1.00 |
| ▸ | GAA | P10253 | 14/20 | 1.00 |
| ▸ | SI | P14410 | 14/20 | 1.00 |
| ▸ | MGAM2 | Q2M2H8 | 14/20 | 1.00 |
| ▸ | PARP1 | P09874 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CBFB | Q13951 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056520 | 0.81 | MGAM (0.68) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL8818813 | 0.81 | MGAM (0.68) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL6511197 | 0.81 | MGAM (1.00) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL11199113 | 0.81 | MGAM (1.00) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL5201397 | 0.81 | MGAM (0.68) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL1170892 | 0.81 | MGAM (0.71) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL6520351 | 0.81 | MGAM (0.67) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL6807332 | 0.79 | MGAM (0.69) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL14012670 | 0.79 | MGAM (0.65) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL11119172 | 0.78 | MGAM (0.63) | MGAMGAASIMGAM2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239767-A1 | Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands | NATIONAL SCIENCE FOUNDATION | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239767-A1 | Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands | TECR, PAICS, DCXR | MGAM 1992/4885GAA 1671/4885SI 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.