Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.55 |
| ▸ | CNR2 | P34972 | 11/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507861 | 0.90 | CNR1 (0.64) | CNR1CNR2KCNH2 | |
| SCHEMBL6510070 | 0.86 | CNR1 (0.55) | CNR1CNR2KCNH2 | |
| SCHEMBL6510954 | 0.86 | CNR1 (0.52) | CNR1CNR2HIF1A | |
| SCHEMBL6511403 | 0.82 | CNR1 (0.55) | CNR1CNR2KCNH2 | |
| SCHEMBL6510603 | 0.81 | CNR1 (0.53) | CNR1CNR2KCNH2 | |
| SCHEMBL6509208 | 0.81 | CNR1 (0.53) | CNR1CNR2KCNH2 | |
| SCHEMBL6509222 | 0.80 | CNR1 (0.52) | CNR1CNR2KCNH2 | |
| SCHEMBL6511462 | 0.79 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL4100584 | 0.70 | CNR1 (0.51) | CNR1HIF1A | |
| SCHEMBL6507469 | 0.68 | CNR1 (0.53) | CNR1CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061505-A1 | BICYCLIC IMIDAZOLYL PYRIMIDIN-4-ONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |