Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | ITGB1 | P05556 | 18/20 | 0.61 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460489 | 0.81 | KMT2A (0.82) | KMT2ANPSR1ITGB1ITGA4CYP2D6 | |
| SCHEMBL6509892 | 0.80 | CNR2 (0.46) | KMT2AITGB1ITGA4MAPT | |
| SCHEMBL6561759 | 0.80 | ITGB1 (0.54) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6627877 | 0.80 | ITGB1 (0.88) | ITGB1ITGA4 | |
| SCHEMBL6561757 | 0.80 | ITGB1 (0.54) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6639157 | 0.80 | ITGB1 (0.80) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6637068 | 0.80 | ITGB1 (0.80) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL27519787 | 0.80 | ITGB1 (0.80) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6563252 | 0.80 | ITGB1 (0.54) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6562648 | 0.80 | ITGB1 (0.54) | ITGB1ITGA4ITGA2ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911451-B1 | Phenylalanine derivatives | CELLTECH R&D LIMITED (GB) | 2005-06-28 | — | — | US | disclosed |