Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 6/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571049 | 0.96 | BTK (0.47) | GAAEPHX1HDAC4HDAC1HDAC6 | |
| SCHEMBL571434 | 0.93 | CA1 (0.43) | GAAEPHX1HDAC4HDAC1HDAC6 | |
| SCHEMBL22506436 | 0.83 | GAA (0.44) | GAAEPHX1HDAC4HDAC1HDAC6 | |
| SCHEMBL4971674 | 0.83 | GAA (0.44) | GAAEPHX1HDAC4HDAC1HDAC6 | |
| SCHEMBL20470280 | 0.83 | GAA (0.44) | GAAEPHX1HDAC4HDAC1HDAC6 | |
| SCHEMBL22535888 | 0.83 | GAA (0.44) | GAAEPHX1HDAC4HDAC1HDAC6 | |
| SCHEMBL4753064 | 0.81 | GAA (0.47) | GAAEPHX1HDAC4HDAC1HDAC6 | |
| SCHEMBL13636231 | 0.81 | GAA (0.47) | GAAEPHX1HDAC4HDAC1HDAC6 | |
| SCHEMBL7264782 | 0.81 | GAA (0.47) | GAAEPHX1HDAC4HDAC1HDAC6 | |
| SCHEMBL22338809 | 0.81 | CA1 (0.51) | GAAEPHX1HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005075426-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS THEREOF | GLENMARK PHARMACEUTICALS LTD. (US) | 2005-08-18 | — | — | WO | claimed |