Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 10/20 | 0.38 |
| ▸ | PPARA | Q07869 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531845 | 0.77 | PPARG (0.61) | FFAR1PPARGPPARAKDR | |
| SCHEMBL4727180 | 0.77 | PPARG (0.57) | PTPN1FFAR1PPARGPPARAMAPT | |
| SCHEMBL8137750 | 0.75 | PPARG (0.51) | FFAR1PPARGPPARA | |
| SCHEMBL8801421 | 0.73 | PPARG (0.50) | PPARGPPARACYP3A4CYP2C9KCNH2 | |
| SCHEMBL170065 | 0.73 | PPARG (0.63) | PPARGPPARACYP3A4CYP2C9KCNH2 | |
| SCHEMBL4283015 | 0.73 | PPARG (0.63) | PPARGPPARACYP3A4CYP2C9KCNH2 | |
| SCHEMBL9721218 | 0.73 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL6506244 | 0.72 | PTPN1 (0.46) | PTPN1FFAR1PPARGPPARACYP2C9 | |
| SCHEMBL4727296 | 0.72 | PPARG (0.47) | FFAR1PPARGPPARAKDR | |
| SCHEMBL12520521 | 0.72 | PPARG (0.65) | PTPN1FFAR1PPARGPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058813-A2 | THIODIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND DIAZOLIDINEDIONE DERIVATIVES AND THEIR USE AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-30 | — | — | WO | claimed |
| WO-2005058813-A2 | THIODIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND DIAZOLIDINEDIONE DERIVATIVES AND THEIR USE AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-30 | — | — | WO | disclosed |